Modeling and simulation techniques have revolutionized the field of drug discovery and development, enabling researchers to gain a deeper understanding of the molecular mechanisms underlying disease and the action of potential therapeutics. In particular, these techniques have proven to be invaluable in the development of large molecules such as biologics, proteins, and peptides. By allowing researchers to visualize and manipulate the structure and function of these complex molecules, modeling and simulation techniques can help to optimize their performance and improve their safety and efficacy.

We have several different types of in silico techniques that can be used for large molecules, including molecular dynamics simulations, quantum mechanics calculations, and homology modeling. Each of these techniques has its own strengths and limitations, and the choice of technique will depend on the specific research question being addressed.